| Safari Adventures: Africa | 2009 | Conspiracy Entertainment | RVL-RFWE-USA | 4.7 |
| Safecracker | 2008 | The Adventure Company | RVL-RQFE-USA | none |
| Saint | 2009 | UFO Interactive | RVL-RZCE-USA | 6.0 |
| Sakura Wars: So Long, My Love | 2010 | NIS America | RVL-SAKE-USA | 6.3 |
| Sam & Max: Beyond Time and Space | 2010 | Atari SA | RVL-R3YE-USA | none |
| Sam & Max: Season One | 2008 | The Adventure Company | RVL-R3XE-USA | none |
| Samba de Amigo | 2008 | Sega | RVL-R3BE-USA | 8.0 |
| Samurai Shodown Anthology | 2009 | SNK Playmore | RVL-RSSE-USA | none |
| Samurai Warriors 3 | 2010 | Nintendo | RVL-S59E-USA | 10.0 |
| Samurai Warriors: Katana | 2008 | Koei | RVL-RS5E-USA | 10.0 |
| Santa Claus is Comin' to Town! | 2011 | Red Wagon Games | RVL-SX5E-USA | 1.0 |
| Satisfashion: Rock the Runway | 2010 | Destineer | RVL-SS5E-USA | none |
| Scarface: The World Is Yours | 2007 | Sierra Entertainment | RVL-RSCE-USA | 7.7 |
| Scene It? Bright Lights! Big Screen! | 2009 | Warner Bros. Interactive Entertainment | RVL-SSCE-USA | 9.0 |
| Scene It? Twilight | 2009 | Konami | RVL-SCNE-USA | none |
| Science Papa | 2009 | Activision | RVL-RZEE-USA | none |
| Scooby-Doo! and the Spooky Swamp | 2010 | Warner Bros. Interactive Entertainment | RVL-SJ2E-USA | none |
| Scooby-Doo! First Frights | 2009 | Warner Bros. Interactive Entertainment | RVL-RQNE-USA | 9.0 |
| Score International Baja 1000: The Official Game | 2008 | Activision | RVL-RJCE-USA | none |
| Sea Monsters: A Prehistoric Adventure | 2007 | DSI Games | RVL-RC7E-USA | none |
| Secret Files: Tunguska | 2010 | Deep Silver | RVL-RTUE-USA | none |
| Secret Saturdays, The: Beasts of the 5th Sun | 2009 | D3Publisher | RVL-R85E-USA | none |
| Sega Bass Fishing | 2008 | Sega | RVL-RBTE-USA | none |
| Sega Superstars Tennis | 2008 | Sega | RVL-RT5E-USA | 9.5 |
| Sengoku Basara: Samurai Heroes | 2010 | Capcom | RVL-SB3E-USA | 8.0 |
| Sesame Street: Cookie's Counting Carnival - The Videogame | 2010 | Warner Bros. Interactive Entertainment | RVL-SS4E-USA | 4.7 |
| Sesame Street: Elmo's A-to-Zoo Adventure - The Videogame | 2010 | Warner Bros. Interactive Entertainment | RVL-SS4E-USA | 1.0 |
| Sesame Street: Elmo's Musical Monsterpiece - The Videogame | 2012 | Warner Bros. Interactive Entertainment | RVL-SSSE-USA | none |
| Sesame Street: Ready, Set, Grover! with Elmo - The Videogame | 2011 | Warner Bros. Interactive Entertainment | RVL-SESE-USA | none |
| Shaun White Skateboarding | 2010 | Ubisoft | RVL-SHNE-USA | 9.0 |
| Shaun White Snowboarding: Road Trip | 2008 | Ubisoft | RVL-RDFE-USA | none |
| Shaun White Snowboarding: Road Trip - Target Edition | 2008 | Ubisoft | RVL-RW7E-USA | 8.0 |
| Shaun White Snowboarding: World Stage | 2009 | Ubisoft | RVL-R6NE-USA | none |
| Shawn Johnson Gymnastics | 2010 | Zoo Games | RVL-SJVE-USA | none |
| Shimano Xtreme Fishing | 2009 | Mastiff | RVL-R39E-USA | none |
| Shiren the Wanderer | 2010 | Atlus | RVL-RFSE-USA | none |
| Shonen Jump One Piece: Unlimited Adventure | 2008 | Namco Bandai Games | RVL-RIPE-USA | none |
| Showtime Championship Boxing | 2007 | DSI Games | RVL-RSYE-USA | none |
| Sid Meier's Pirates! | 2010 | 2K Games | RVL-SIDE-USA | none |
| Silent Hill: Shattered Memories | 2009 | Konami | RVL-R5WE-USA | 6.8 |
| SimAnimals | 2009 | Electronic Arts | RVL-R4AE-USA | 5.5 |
| SimAnimals: Africa | 2009 | Electronic Arts | RVL-R7AE-USA | none |
| SimCity Creator | 2008 | EA Games | RVL-R4CE-USA | 8.5 |
| Simpsons Game, The | 2007 | EA Games | RVL-RSNE-USA | none |
| Sims 2, The: Castaway | 2007 | Electronic Arts | RVL-R42E-USA | 9.5 |
| Sims 2, The: Pets | 2007 | EA Games | RVL-R4PE-USA | 6.0 |
| Sims 3, The | 2010 | Electronic Arts | RVL-S3ME-USA | 6.4 |
| Sin & Punishment: Star Successor | 2010 | Nintendo | RVL-R2VE-USA | 8.5 |
| Sing 4: The Hits Edition | 2011 | Crave | RVL-SIHE-USA | none |
| Six Flags Fun Park | 2009 | Ubisoft | RVL-R6FE-USA | 10.0 |
| Skate City Heroes | 2008 | Zoo Games | RVL-RHUE-USA | none |
| Skate It | 2008 | Electronic Arts | RVL-RVSE-USA | none |
| Ski and Shoot | 2008 | Conspiracy Entertainment | RVL-RUME-USA | none |
| Ski-Doo Snowmobile Challenge | 2009 | Valcon Games | RVL-R87E-USA | none |
| Sky Crawlers, The: Innocent Aces | 2010 | XSEED Games | RVL-RQRE-USA | none |
| Skylanders: Giants | 2012 | Activision | RVL-SKYE-USA | 9.0 |
| Skylanders: Spyro's Adventure | 2011 | Activision | RVL-SSPE-USA | 6.0 |
| Skylanders: SuperChargers Racing | 2015 | Activision | RVL-SKNE-USA | 7.5 |
| Skylanders: Swap Force | 2013 | Activision | RVL-SVXE-USA | 7.0 |
| Skylanders: Trap Team | 2014 | Activision | RVL-SK8E-USA | 7.0 |
| Sled Shred featuring the Jamaican Bobsled Team | 2010 | SouthPeak Games | RVL-R9YE-USA | none |
| Sleepover Party | 2010 | Ubisoft | RVL-R9LE-USA | none |
| Smart Series Presents: Jaja's Adventure | 2010 | Tommo | RVL-R67E-USA | none |
| Smarty Pants: Trivia Fun for Everyone! | 2007 | Electronic Arts | RVL-RP2E-USA | none |
| Smiley World: Island Challenge | 2009 | Zoo Digital Publishing | RVL-RIDE-USA | 5.0 |
| Smurfs 2, The | 2013 | Ubisoft | RVL-S2XE-USA | 2.0 |
| Smurfs, The: Dance Party | 2011 | Ubisoft | RVL-SDUE-USA | 2.0 |
| Smurfs, The: Dance Party - Walmart Edition | 2011 | Ubisoft | RVL-SDUX-USA | 1.0 |
| Sniper Elite | 2010 | Maximum Family Games | RVL-SSNE-USA | none |
| SNK Arcade Classics Vol. 1 | 2008 | SNK Playmore | RVL-RNCE-USA | none |
| Solitaire & Mahjong | 2009 | Crave | RVL-RSOE-USA | 1.0 |
| Sonic & Sega All-Stars Racing | 2010 | Sega | RVL-R3RE-USA | 9.3 |
| Sonic and the Black Knight | 2009 | Sega | RVL-RENE-USA | 7.8 |
| Sonic and the Secret Rings | 2007 | Sega | RVL-RSRE-USA | 8.4 |
| Sonic Colors | 2010 | Sega | RVL-SNCE-USA | 9.1 |
| Sonic Riders: Zero Gravity | 2008 | Sega | RVL-RS9E-USA | 9.4 |
Sonic Unleashed  | 2008 | Sega | RVL-RSVE-USA | 8.2 |
| Soulcalibur Legends | 2007 | Namco Bandai Games | RVL-RSLE-USA | 7.3 |
| Space Camp | 2009 | Activision | RVL-RIYE-USA | none |
| Space Chimps | 2008 | Brash Entertainment | RVL-RP9E-USA | 10.0 |
| Spectrobes: Origins | 2009 | Disney Interactive Studios | RVL-RXXE-USA | 9.0 |
| Speed | 2010 | Zoo Games | RVL-SPEE-USA | 7.0 |
| Speed Racer: The Videogame | 2008 | Warner Bros. Interactive Entertainment | RVL-R3PE-USA | 10.0 |
| Speed Zone | 2009 | Detn8 | RVL-RZSE-USA | none |
| Spider-Man 3 | 2007 | Activision | RVL-RS3E-USA | 8.0 |
| Spider-Man: Edge of Time | 2011 | Activision | RVL-SQME-USA | 8.5 |
| Spider-Man: Friend or Foe | 2007 | Activision | RVL-RFOE-USA | 8.5 |
| Spider-Man: Shattered Dimensions | 2010 | Activision | RVL-SPDE-USA | 9.0 |
| Spider-Man: Web of Shadows | 2008 | Activision | RVL-R3SE-USA | 8.3 |
| Spiderwick Chronicles, The | 2008 | Sierra Entertainment | RVL-R48E-USA | none |
| Spore Hero | 2009 | EA Games | RVL-RQOE-USA | 10.0 |
| SPRay | 2008 | Tecmo | RVL-RYIE-USA | none |
| Spy Fox in Dry Cereal | 2008 | Majesco | RVL-RDLE-USA | none |
| Spy Games: Elevator Mission | 2007 | UFO Interactive | RVL-RECE-USA | 2.5 |
| Spyborgs | 2009 | Capcom | RVL-RSWE-USA | none |
| Squeeballs Party | 2009 | Performance Designed Products | RVL-R6YE--USA | 4.0 |
| SSX Blur | 2007 | EA Sports Big | RVL-RSXE-USA | 2.0 |
| Star Trek: Conquest | 2007 | Bethesda Softworks | RVL-RTJE-USA | none |
| Star Wars: The Clone Wars - Lightsaber Duels | 2008 | LucasArts | RVL-RLFE-USA | 8.0 |
| Star Wars: The Clone Wars - Republic Heroes | 2009 | LucasArts | RVL-RQLE-USA | none |
| Star Wars: The Force Unleashed | 2008 | LucasArts | RVL-RSTE-USA | 9.0 |
| Star Wars: The Force Unleashed II | 2010 | LucasArts | RVL-SFUE-USA | none |
| Story Hour: Adventures | 2008 | Zoo Games | RVL-R3AE-USA | 4.0 |
| Story Hour: Fairy Tales | 2008 | Zoo Games | RVL-R4FE-USA | none |
| Storybook Workshop | 2009 | Konami | RVL-R4VE-USA | none |
| Summer Athletics: The Ultimate Challenge | 2008 | Conspiracy Entertainment | RVL-RU3E-USA | none |
| Summer Sports 2: Island Sports Party | 2008 | Destineer | RVL-RI6E-USA | none |
| Summer Sports: Paradise Island | 2008 | Destineer | RVL-RSUE-USA | none |
| Summer Stars 2012 | 2012 | Deep Silver | RVL-SSJE-USA | none |
| Super Fruit Fall | 2007 | Codemasters | RVL-RF4E-USA | none |
| Super Mario All-Stars | 2010 | Nintendo | RVL-SVME-USA | 7.6 |
| Super Mario Galaxy | 2007 | Nintendo | RVL-RMGE-USA | 8.9 |
| Super Mario Galaxy 2 | 2010 | Nintendo | RVL-SB4E-USA | 8.9 |
| Super Monkey Ball: Banana Blitz | 2006 | Sega | RVL-RSME-USA | 8.8 |
| Super Monkey Ball: Step & Roll | 2010 | Sega | RVL-SMBE-USA | 8.0 |
| Super Paper Mario | 2007 | Nintendo | RVL-R8PE-USA | 9.2 |
| Super PickUps | 2008 | XS Games | RVL-RQUE-USA | 4.0 |
| Super Smash Bros. Brawl | 2008 | Nintendo | RVL-RSBE-USA | 8.7 |
| Super Sonic Racer | 2011 | Zoo Games | RVL-SRSE-USA | 1.0 |
| Super Swing Golf | 2006 | Tecmo | RVL-RPYE-USA | none |
| Super Swing Golf Season 2 | 2007 | Tecmo | RVL-R2PE-USA | 9.0 |
| Surf's Up | 2007 | Ubisoft | RVL-RXUE-USA | 4.0 |
| Survivor | 2010 | Valcon Games | RVL-RLNE-USA | none |
| Swords | 2010 | Majesco | RVL-SSZE-USA | 6.0 |
